Can folate cause depression?
Can folate cause depression? What the Studies Have Found. A review of 11 studies involving 15,315 people found an association between low folic acid levels and depression, adding to the evidence that folic acid deficiency is a risk factor for depression. Researchers have also focused on people who are being treated for depression. Is folate good for depression? Folate may be useful in the treatment of depression in individuals with elevated homocysteine and with mutations in the MTHFR gene, such as a homozygous 677 TT mutation. Lower levels of folate are associated with a poor response to antidepressants while higher...