What functional groups are in sumatriptan?

What functional groups are in sumatriptan?

Sumatriptan is a sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family).

What is sumatriptan classified as?

Sumatriptan belongs to a class of drugs known as triptans. It affects a certain natural substance (serotonin) that causes narrowing of blood vessels in the brain. It may also relieve pain by affecting certain nerves in the brain.

Are triptans serotonin agonists?

Triptans are used as abortive medications for moderately severe to severe migraine headaches. These drugs are selective serotonin agonists, specifically acting at 5-hydroxytryptamine 1B/1D (5-HT1B/1D) receptors on intracranial blood vessels and sensory nerve endings.

What is the mechanism of action of sumatriptan Imitrex )?

Sumatriptan is in a class of medications called selective serotonin receptor agonists. It works by narrowing blood vessels in the head, stopping pain signals from being sent to the brain, and blocking the release of certain natural substances that cause pain, nausea, and other symptoms of migraine.

Is sumatriptan a stimulant?

Sumatriptan works by stimulating serotonin receptors in the brain, which causes the muscles surrounding the blood vessels in the brain to contract. Sumatriptan also stabilises some of the chemical changes in the brain during a migraine attack, which alleviates migraine symptoms.

Is sumatriptan a psychotropic drug?

Sumatriptan was psychoactive, was discriminated from placebo, produced a dose-related decrease on euphoria scores, elevated scores on measures of apathetic sedation and disliking, and lacked identification as a prototypic drug of abuse.

Can triptans cause liver damage?

Reported cases of hepatotoxicity from the triptans have been mild-to-moderate in severity, accompanied by symptoms and jaundice, but without acute liver failure, chronic hepatitis or vanishing bile duct syndrome.

How do triptans make you feel?

The most common include: A warm-hot sensation, tightness, tingling, flushing, and feelings of heaviness or pressure in areas such as the face, arms, legs and occasionally the chest. Triptan sensations in the chest can mimic heart pains (angina) and may cause alarm.

Does sumatriptan make you tired?

Common side effects include feeling or being sick, feeling sleepy or dizzy. Do not take migraine medicines such as ergotamine or other triptans when taking sumatriptan.

Is sumatriptan a sedating?

Sumatriptan can cause adverse central nervous system events outside migraine attacks. It can cause mild sedative effects such as sleepiness or fatigue.