Common questions

What is benzothiazole used for?

What is benzothiazole used for?

Benzothiazole and its derivatives (BTs) are high production volume chemicals that have been used for several decades in a large number of industrial and consumer products, including vulcanization accelerators, corrosion inhibitors, fungicides, herbicides, algicides, and ultraviolet (UV) light stabilizers.

What is C7H5NS?

Benzothiazole | C7H5NS – PubChem.

Is Benzothiazole soluble in water?

Benzotriazoles and benzothiazoles are highly water soluble and are difficult to remove via conventional water treatment, suggesting that they may be ubiquitous in the environment (Richardson, 2009).

Is benzothiazole aromatic?

Benzothiazole is an aromatic heterocyclic compound consisting of a five- membered 1,3-thiazole ring fused to a benzene ring. The nine atoms of the bicyclic structure and the attached substituents are coplanar.

What is the chemical name of Benzothiazole?

Benzothiazole

Names
Preferred IUPAC name 1,3-Benzothiazole
Identifiers
CAS Number 95-16-9
3D model (JSmol) Interactive image

What is thiazole ring?

Thiazole, or 1,3-thiazole, is a heterocyclic compound that contains both sulfur and nitrogen; the term ‘thiazole’ also refers to a large family of derivatives. The thiazole ring is notable as a component of the vitamin thiamine (B1).

Is thiazole ring is present in the niacin vitamin?

The thiazole ring is notable as a component of the vitamin thiamine (B1)….Thiazole.

Names
Chemical formula C3H3NS
Molar mass 85.12 g·mol−1
Boiling point 116 to 118 °C (241 to 244 °F; 389 to 391 K)
Acidity (pKa) 2.5 (of conjugate acid)

Which nitrogen in pyrazole is basic?

In order to quickly refresh your memory, a “pyrrole-like” nitrogen is a non-basic nitrogen, with a lone pair involved in aromaticity, but rather acidic (can be deprotonated quite easily, i.e with NaH) whereas the “pyridine-like” nitrogen has a lone pair on a sp2 orbital and is therefore basic and nucleophilic.

What type of inhibitor is pyrazole?

Pyrazole and its analogues are widely used to inhibit alcohol dehydrogenase and to block the metabolism of ethanol. Experiments were conducted to demonstrate that pyrazole is oxidized to 4-hydroxypyrazole by isolated rat liver microsomes.

How is benzothiazole prepared as a food additive?

Benzothiazoles are prepared by treatment of 2-mercaptoaniline with acid chlorides: Benzothiazole occurs naturally in some foods but is also used as a food additive. It has a sulfurous odor and meaty flavor. The European Food Safety Authority assessment had “no safety concern at estimated levels of intake as a flavouring substance”.

Which is the ring closure of benzothiazoles?

Benzothiazoles are most commonly prepared by the ring closure of o -aminobenzothiazoles. This methodology has been well reviewed in both CHEC (1984) <1984CHEC (6)235> and CHEC-II (1996) <1996CHEC-II (3)373>.

How is benzothiazole related to thiazoles and arsenic?

A benzothiazole derivative is suggested as a dye for arsenic detection. Benzothiazoles are related to thiazoles, which lack the fused benzene ring.

How are target compounds synthesized in benzothiazole scaffold?

In all, target compounds were synthesized following a green synthetic strategy using water as the reaction medium to construct the benzothiazole scaffold followed by (i) microwave-assisted catalyst-free and (ii) ammonium chloride-catalyzed solvent-free amide coupling.

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Ruth Doyle