What is adenocarcinoma situ?
What is adenocarcinoma situ?
Listen to pronunciation. (A-deh-noh-KAR-sih-NOH-muh in SY-too) A condition in which abnormal cells are found in the glandular tissue that lines certain internal organs, such as the uterus, cervix, lung, pancreas, and colon.
Is adenocarcinoma in situ malignant?
Adenocarcinoma in situ (AIS) means that there are abnormal cells in these mucus-producing glands, but they aren’t cancerous and have not spread. If left untreated, these abnormal cells could become cancer.
Is carcinoma in situ considered cancer?
Carcinoma in situ refers to cancer in which abnormal cells have not spread beyond where they first formed. The words “in situ” mean “in its original place.” These in situ cells are not malignant, or cancerous. However, they can sometime become cancerous and spread to other nearby locations.
What is an in situ carcinoma?
Carcinoma in situ (CIS) is a group of abnormal cells that are found only in the place where they first formed in the body (see left panel). These abnormal cells may become cancer and spread to nearby normal tissue (see right panel).
What causes adenocarcinoma in situ?
What causes adenocarcinoma in situ? Most cases of AIS and endocervical adenocarcinoma in the cervix are a result of the normal endocervical cells in the cervix becoming infected with a high-risk type of virus called human papillomavirus (HPV).
What is the treatment for adenocarcinoma in situ?
The standard treatment for cervical adenocarcinoma in situ (AIS) is hysterectomy, which is a more aggressive treatment than that used for squamous intraepithelial lesions.
What causes carcinoma in situ?
It’s not clear what causes DCIS. DCIS forms when genetic mutations occur in the DNA of breast duct cells. The genetic mutations cause the cells to appear abnormal, but the cells don’t yet have the ability to break out of the breast duct.
Can adenocarcinoma in situ come back?
Recurrence risk of AIS is only 2.6% with negative margins but increases to 19% when margins are positive. Adenocarcinoma in situ is also associated with “skip lesions”—foci of adenocarcinoma cells that are not contiguous.
What does it mean to have adenocarcinoma in situ?
Adenocarcinoma in situ (Concept Id: C0334276) A lesion in which the normally situated glands are partially or completely replaced by atypical cells with malignant characteristics. Adenocarcinoma in situ
When to use PET or CT for adenocarcinoma in situ?
Adenocarcinomas in situ are commonly associated with PET false-negative results. FDG PET/CT is recommended when assessing subsolid ground-glass lung lesions that have a solid component measuring more than 8 mm 5.
Are there any exceptions to carcinoma in situ?
Exceptions include CIS of the colon (polyps), the bladder (preinvasive papillary cancer), or the breast (ductal carcinoma in situ or lobular carcinoma in situ).
How is ductal carcinoma in situ ( DCIS ) diagnosed?
Ductal carcinoma in situ ( DCIS ), also known as intraductal carcinoma, is a pre-cancerous or non-invasive cancerous lesion of the breast. DCIS is classified as Stage 0. It rarely produces symptoms or a breast lump one can feel, and is usually detected through screening mammography.
