What is jelliffe equation?
What is jelliffe equation?
Jelliffe’s equation Estimated GFR = {(Volume of distribution × (Serum creatinine on day 1 − Serum creatinine on day 2)} + Creatinine production) 100/1,440/Average serum creatinine [29, 30].
Can losing weight lower creatinine levels?
Both fat and lean body mass decrease with weight loss, and reduction in muscle mass could lead to lower serum creatinine levels and, thus, higher eGFR. These effects are more pronounced with surgical weight loss than the modest weight loss achieved with lifestyle modifications and medications.
What does GFR 60 mean?
A GFR of 60 or higher is in the normal range. A GFR below 60 may mean kidney disease. A GFR of 15 or lower may mean kidney failure.
Which is better GFR or creatinine clearance?
Creatinine clearance exceeds GFR because creati- nine is secreted by the proximal tubule as well as filtered by the glomerulus. Creatinine clearance can be measured from serum creatinine and cre- atinine excretion, or estimated from serum cre- atinine using estimating equations.
How to calculate GFR using the Jelliffe method?
Formulas to calculate Glomerular Filtration Rate (Jelliffe Method): GFR for male : [ 98 – 0.8 x (age – 20) ] x BSA / [1.73 x Serum Creatinine] GFR for female :GFR (females) = GFR (males) x 0.9 where, BSA= Body Surface Area.
How does the Jelliffe equation relate to renal dysfunction?
Abnormal increases in CrCl may be indicative of some kind of renal dysfunction, either of filtration, existence of infection, reduced blood flow, dehydration or muscular problems. The Jelliffe equation does not require a patient’s height or weight because it describes unstable renal function normalized to a body surface area of 1.73 m 2.
Which is greater the Wright or Cockroft-Gault-Jelliffe formula?
The Wright formula overestimated GFR in the range of GFR <50 ml/min and underestimated in the higher range (GFR >120 ml/min). The bias was greater using the Cockroft–Gault and Jelliffe formulae, as shown in Table 2, which ranged from 12% to 23% and from 15% to 32%, respectively.
Which is the correct equation for the Jelliffe equation?
The estimated creatinine clearance rate (eCCr) based on the 1973 equation by Jelliffe is: eCCr = ( (98 – 0.8 x (Age – 20)) x (1 – (0.1 x Gender)) x (BSA/1.73)) / (Serum creatinine in µmol/L x 0.0113) CrCl normal values are around 97-137 ml/min in men and 88-128 mL/min in women.
