What is another name for systemic lupus?
What is another name for systemic lupus?
What is SLE? Systemic lupus erythematosus (SLE), is the most common type of lupus. SLE is an autoimmune disease in which the immune system attacks its own tissues, causing widespread inflammation and tissue damage in the affected organs.
What is the major complication of systemic lupus erythematosus?
Lupus can cause serious kidney damage, and kidney failure is one of the leading causes of death among people with lupus. Brain and central nervous system. If your brain is affected by lupus, you may experience headaches, dizziness, behavior changes, vision problems, and even strokes or seizures.
How does systemic lupus affect the CNS and PNS?
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disorder with wild spectrum of clinical presentations. It affects both the central (CNS) and the peripheral nervous system (PNS). The American College of Rheumatology described cases definitions and classification criteria for 19 CNS and PNS syndromes observed in SLE [ 1 ].
How does systemic lupus erythematosus ( SLE ) affect the body?
Systemic lupus erythematosus (SLE), is the most common type of lupus. SLE is an autoimmune disease in which the immune system attacks its own tissues, causing widespread inflammation and tissue damage in the affected organs. It can affect the joints, skin, brain, lungs, kidneys, and blood vessels.
Are there any new drugs for systemic lupus erythematosus?
SLE treatment consists primarily of immunosuppressive drugs that inhibit activity of the immune system. Hydroxychloroquine and corticosteroids (e.g., prednisone) are often used to treat SLE. The FDA approved belimumab in 2011, the first new drug for SLE in more than 50 years.
What causes flares in patients with systemic lupus?
Further, several drugs such as the sulfa-drugs are well known to cause flares in patients with SLE. Ultraviolet rays and sun exposure leads to increased cell apoptosis and is one of the well-known triggers for SLE. Several viral infections have been implicated, the underlying mechanism thought to be molecular mimicry.
