What is a positive Immunofixation?
What is a positive Immunofixation?
Positive results from the test indicate the presence of abnormal Ig. This may suggest the existence of an underlying health condition, such as: an immune system disorder. multiple myeloma. Waldenstrom’s macroglobulinemia.
What is test for Immunofixation serum for?
The Immunofixation (IFE) Serum Test detects and identifies monoclonal immunoglobulin gammopathies, which may indicate conditions such as multiple myeloma or Waldenstrom’s macroglobulinemia.
What is considered high level of IgM?
Normal
| IgA | 60–400 milligrams per deciliter (mg/dL) or 600–4,000 milligrams per liter (mg/L) |
|---|---|
| IgG | 700–1,500 mg/dL or 7.0–15.0 grams per liter (g/L) |
| IgM | 60–300 mg/dL or 600–3,000 mg/L |
| IgD | 0–14 mg/dL or 0–140 mg/L |
| IgE | 3–423 international units per milliliter (IU/mL) or 3–423 kilo-international units per liter (kIU/L) |
Why would a doctor order an Immunofixation test?
This test is most often used to help diagnose or monitor a variety of different conditions. These include: Multiple myeloma, a cancer of the white blood cells. Other forms of cancer, such as lymphoma (cancer of the immune system) or leukemia (cancer of blood-forming tissues, such as bone marrow)
Is Immunofixation the same as electrophoresis?
Urine protein electrophoresis (UPEP) is used to identify the presence of the Bence Jones protein in urine. Immunofixation is used to identify the subtype of protein (ie, IgA lambda).
What is an abnormal protein band?
When an abnormal band on either a serum or a urine electrophoresis pattern suggests the presence of a single type of immunoglobulin (monoclonal), immunofixation electrophoresis (IFE) or immunosubtraction electrophoresis can be used as follow-up tests to further identify abnormal proteins.
What is Immunofixation result?
Immunofixation can either reveal a normal pattern or identify a monoclonal protein or a polyclonal immunoglobulin pattern. A normal result includes a darker immunoglobulin G (IgG) lane, a lighter immunoglobulin A (IgA), an absent immunoglobulin M (IgM), and a denser kappa compared to lambda lane, with ratio of 2:1.
What is IgM in blood test results?
Immunoglobulin M (IgM), which is found mainly in the blood and lymph fluid, is the first antibody to be made by the body to fight a new infection. Immunoglobulin E (IgE), which is associated mainly with allergic reactions (when the immune system overreacts to environmental antigens such as pollen or pet dander).
