What drugs interact with glucocorticoids?

What drugs interact with glucocorticoids?

What drugs interact with corticosteroids?

Some key drugs that interact with steroids include anticoagulants (such as warfarin), drugs for blood pressure, antiepileptics, antidiabetic drugs, antifungal drugs, bronchodilators (such as salbutamol) and diuretics.

What drugs should not be taken with corticosteroids?

(e.g. digitalis) drugs resulting in decreased cortisone in the blood (e.g. rifampicin, carbamazepine, phenobarbital, phenytoin, primidone) or decrease the gastrointestinal absorption of cortisone (e.g. gastric dressing) lithium (corticosteroids decrease blood levels of lithium)

Who should not take glucocorticoids?

Both naturally produced and synthetic glucocorticoids have two main functions: Regulation of sugar metabolism….Avoid glucocorticoids if you:

• Are allergic to glucocorticoids.
• Are taking medications for a fungal infection.
• Have an infection of malaria in the brain.

What drugs should not be taken with lithium?

Avoid taking lithium supplements and NSAIDs at the same time. Some NSAIDs include ibuprofen (Advil, Motrin, Nuprin, others), indomethacin (Indocin), naproxen (Aleve, Anaprox, Naprelan, Naprosyn), piroxicam (Feldene), aspirin, and others.

What drugs interact with dexamethasone?

Examples of drugs that can cause interactions with dexamethasone are listed below.

• Antibiotics.
• Antifungal drugs.
• Blood thinners.
• Cholesterol drugs.
• Cushing’s syndrome drugs.
• Diabetes drugs.
• Diuretics (water pills)
• Epilepsy drugs.

What drugs can you not take with prednisone?

Some products that may interact with this drug include: aldesleukin, mifepristone, drugs that can cause bleeding/bruising (including antiplatelet drugs such as clopidogrel, “blood thinners” such as dabigatran/warfarin, NSAIDs such as aspirin/celecoxib/ibuprofen).

What are the contraindications of corticosteroids?

Contraindications to corticosteroids include hypersensitivity to any component of the formulation, concurrent administration of live or live-attenuated vaccines (when using immunosuppressive dosages), systemic fungal infection, osteoporosis, uncontrolled hyperglycemia, diabetes mellitus, glaucoma, joint infection.

Which are contraindications to the administration of glucocorticoid drugs?

Can glucocorticoid cause high blood pressure?

Endogenous glucocorticoids are known to increase blood pressure, but very little is known about the early effects of synthetic glucocorticoids (eg, prednisone, dexamethasone) on blood pressure. Objective: To assess longitudinal variations of blood pressure before and after initiation of systemic glucocorticoid therapy.

How do NSAIDs interact with lithium?

When combined with lithium, NSAIDs can increase lithium levels in the blood resulting in an increased risk for serious adverse effects like confusion, tremor, slurred speech, and vomiting. Examples of non-prescription NSAIDs include: Ibuprofen (Advil® or Motrin®)

Are there any side effects to taking glucocorticoids?

However, more regular or extended dosing has been associated with a number of severe side effects. If glucocorticoids are given on a daily basis (at a dose equivalent to prednisone 15mg/day for more than three weeks), the adrenal glands stop producing glucocorticoids and tissue in the adrenal cortex begins to atrophy (die off).

When to take extra doses of glucocorticoids?

For people who are taking glucocorticoids long-term, extra doses of glucocorticoids should be given during times of acute stress, such as severe infection or surgery, to mimic the cortisol surge that is normally produced by the body during particularly stressful events, otherwise healing may be delayed or incomplete.

Why do you need a glucocorticoid in your body?

Drugs that turn down your immune system, such as glucocorticoids, can keep your body from rejecting the new organ. A glucocorticoid is a kind of steroid. The type you need depends on the specific health condition you have. How glucocorticoids affect you will depend on the specific drug or the dose you take.

How are glucocorticoids similar to the hormone cortisol?

[1] Glucocorticoids (GCs) are a group of drugs structurally and pharmacologically similar to the endogenous hormone cortisol with various functions like anti-inflammatory, immunosuppressive, anti-proliferative, and vaso-constrictive effects. Their actions are used medically for the treatment of various conditions indicated below.