Is Dysgerminoma a teratoma?

Dysgerminoma: This is the most common type of malignant ovarian germ cell tumor. Mature teratoma (dermoid cyst or ovarian cyst): This is the most common type of benign ovarian germ cell tumor. These noncancerous tumors usually grow in teenage girls and young women.

How is Dysgerminoma diagnosed?

The diagnosis of dysgerminomas requires either laparoscopy or laparotomy. The choice of surgical approach depends on clinical findings and imaging and laboratory results, as well as an index of suspicion for malignancy.

What is the tumor marker for Dysgerminoma?

Most dysgerminomas are associated with elevated serum lactic dehydrogenase (LDH), which is sometimes used as a tumor marker.

What are the symptoms of germ cell cancer?

Common signs of germ cell tumors include:

A mass on your ovaries or testicles.
Belly pain and swelling (caused by tumor)
Bathroom troubles (a hard time pooping or holding in your pee, if the tumor is near your pelvis)
Breast growth, pubic hair, or vaginal bleeding at an earlier age than normal.
Belly or chest pain.

What is a dysgerminoma?

(DIS-jer-mih-NOH-muh) A type of cancer that begins in germ cells in females. Germ cells are cells that form sperm in males or eggs in females. Dysgerminomas occur most often in the ovaries, but they may also occur in other areas of the body, including the central nervous system.

Are dysgerminoma radiosensitive?

Ovarian dysgerminoma is a highly radiosensitive malignant tumor occurring in young age group. The conventional treatment was total abdominal hysterectomy and bilateral salpingo-oophorectomy followed by radiotherapy.

What does dysgerminoma mean?

Are teratomas usually benign or malignant?

Mature teratomas tend to be benign, or non-cancerous. Mature teratomas can present in different ways. They may be: Solid – made of tissue, but not enclosed.

Is dysgerminoma curable?

This treatment produces less morbidity than chemotherapy and will cure approximately two-thirds of patients. Chemotherapy should be used for salvage of subsequent relapse. Both radiation and chemotherapy are highly effective treatment modalities for dysgerminoma.

Why is LDH elevated in dysgerminoma?

Since LDH is a glycolytic enzyme it may be abundant in dysgerminoma cells. Changes in the permeability of the tumor cell membranes or necrosis of tumor cells may release enzymes into the circulation, but in such cases one should expect other enzymes to be as markedly elevated as LDH.

What are the signs and symptoms of a teratoma?

Such symptoms include constipation and increased frequency of stools or urinary tract infections. In rare cases, sacrococcygeal tumors cause partial paralysis (paresis) of the legs and tingling or numbness (paresthesia). The signs and symptoms of sacrococcygeal teratoma depend largely on the size and location of the tumor.

What are the different types of teratoma cells?

Teratoma is a type of germ cell tumor that may contain several different types of tissue, such as hair, muscle, and bone. Teratomas may be mature or immature, based on how normal the cells look under a microscope.

What’s the difference between seminoma and teratoma cancer?

For malignant teratomas, chemotherapy is given after the surgery. Seminoma. It is the most treatable and curable cancer in the testis. It usually originates from the germinal epithelium of the seminiferous tubules. 50% of the germ cell tumors in the testis are seminoma.

What do symptoms of dysgerminoma look like?

When dissected, they look white and homogeneous and sometimes have necrotic areas. Dysgerminoma are almost totally symptoms free or asymptomatic in the early stages. Abnormal bleeding during menstruation should raise alarm and suspicion but again non-specific.

Is Dysgerminoma a teratoma?