What is the Selena Sledai score?
What is the Selena Sledai score?
The SELENA-SLEDAI consists of 24 items (nine organ systems) that are scored based on presence at the time of visit or in the preceding 10 days. The scoring is additive across items, with a possible total score range of 0 to 105 (higher scores represent greater disease activity).
What is a lupus index?
The Systemic Lupus Erythematosus Disease Activity Index (SLEDAI) was developed and validated as a clinical index for the measurement of disease activity in SLE and has been used as a global measure of disease activity in SLE since its intro- duction in 19851,2. This index was modeled on clinicians’ global judgment.
How is disease activity measured in SLE?
Two main types of activity measures in SLE have been developed: global score systems (for example, the European Consensus Lupus Activity Measurements, Systemic Lupus Activity Measure [SLAM], and Systemic Lupus Erythematosus Disease Activity Index [SLEDAI]), which provide an overall measure of activity, and individual …
How do you read a Sledai?
A SLEDAI score greater than or equal to 3 points and a greater than or equal to 1-point increase in PGA (range 0-3) is considered mild/moderate flare. A SLEDAI score greater than or equal to 12 points, and a greater than or equal to 2.5-point increase in PGA is included for severe flare.
What is the total score for SELENA SLEDAI?
patient’s SELENA-SLEDAI total score is the sum of all marked SLE-related descriptors. A total score can fall between 0 and 105, with a higher score representing a more significant degree of disease activity.1,2 Trademarks are owned by or licensed to the GSK group of companies.
How is SELENA SLEDAI used to diagnose SLE?
SELENA-SLEDAI has been shown to be a validated tool for measuring disease activity in patients with SLE. This assessment can be completed to objectively assess the patient’s current state of disease. All SLE-related descriptors that are present at the time of the visit or within the previous 10 days should be checked off on the form.1,2
How is the SLE disease activity index ( SLEDAI ) calculated?
It is based on the SLEDAI 2000 or SLEDAI 2K score, a modification of the original SLEDAI score. This type of index is the most commonly used and one of the two major scoring systems (along BILAG) that evaluate the activity of lupus erythematosus. The SLEDAI score calculator consists of a list of 24 items, 16 clinical and 8 laboratory results.
What’s the maximum SLEDAI score for a disease?
The SLEDAI and its modifications measure disease activity based on 24 questions assessing the clinical manifestations of SLE, including physical findings and laboratory values weighted across organ systems.7 Although the maximum score achievable is 105, even with very active disease, scores rarely exceed 20.