What is the characteristics of Bordetella pertussis?
What is the characteristics of Bordetella pertussis?
CHARACTERISTICS: Bordetella pertussis are small, gram-negative, encapsulated, non-motile, coccobacilli with outer pili. They are generally about 0.5-1.0 µm in size 3- 5. Some have reported that the bacteria are covered with surface slime or biofilm composed of carbohydrates 6 .
What bacteria causes Bordetella?
Pertussis, a respiratory illness commonly known as whooping cough, is a very contagious disease caused by a type of bacteria called Bordetella pertussis. These bacteria attach to the cilia (tiny, hair-like extensions) that line part of the upper respiratory system.
What type of organism is Bordetella pertussis?
Bordetella pertussis is a Gram-negative, aerobic, pathogenic, encapsulated coccobacillus of the genus Bordetella, and the causative agent of pertussis or whooping cough. Like B. bronchiseptica, B. pertussis is motile and expresses a flagellum-like structure.
Where is the bacteria Bordetella pertussis?
Pertussis is also known as whooping cough. It is a highly infectious bacterial disease involving the respiratory tract. It is caused by a bacterium (Bordetella pertussis or Bordetella Parapertussis ) that is found in the mouth, nose and throat of an infected person.
What does Bordetella pertussis look like?
Bordetella pertussis is a small (approximately 0.8 μm by 0.4 μm), rod-shaped, coccoid, or ovoid Gram-negative bacterium that is encapsulated and does not produce spores. It is a strict aerobe. It is arranged singly or in small groups and is not easily distinguished from Haemophilus species.
What are the four methods used to identify Bordetella pertussis?
Common laboratory diagnostic methods used for pertussis diagnosis include culture, direct-fluorescent-antibody testing (DFA), serology and polymerase chain reaction (PCR). Culture of Bordetella pertussis is highly specific but fastidious and has limited sensitivity.
What does Bordetella pertussis cause?
Pertussis, also known as whooping cough, is a highly contagious respiratory disease. It is caused by the bacterium Bordetella pertussis. Pertussis is known for uncontrollable, violent coughing which often makes it hard to breathe.
What color is Bordetella pertussis?
Bordetella pertussis and Bordetella parapertussis are small, shiny, round and mercury silver in color on Regan-Lowe Agar. With extended incubation, the colonies become whitish-gray.
What is Bordetella serology?
Serology for Bordetella pertussis. Pertussis serology provides suggestive evidence of infection when there is a compatible clinical presentation and no history of recent pertussis vaccination. Positive result is indicated by any of the following: Seroconversion or a fourfold or greater rise in Bordetella pertussis …
What is Bordetella PCR?
PCR is a molecular technique used to detect DNA sequences of the Bordetella pertussis bacterium and unlike culture, does not require viable (live) bacteria present in the specimen. Despite these advantages, PCR can give results that are falsely-negative or falsely-positive.
Is Bordetella pertussis fastidious?
Bordetella pertussis is a fastidious gram-negative coccobacillus responsible for the respiratory infection commonly known as “whooping cough.” The organism is spread by respiratory droplets and is highly contagious among close contacts. The typical incubation period is 7 to 10 days, but it may be as long as 21 days.
What are the pathogenic mechanisms of Bordetella pertussis?
These virulence factors include adhesins such as filamentous haemagglutinin, fimbriae and pertactin, which allow B. pertussis to bind to ciliated epithelial cells in the upper respiratory tract.
