What is hepatitis B antigen positive?
What is hepatitis B antigen positive?
HBsAg (Hepatitis B surface antigen) – A “positive” or “reactive” HBsAg test result means that the person is infected with hepatitis B. This test can detect the actual presence of the hepatitis B virus (called the “surface antigen”) in your blood.
What is HBe antibody?
Hepatitis B e antibody is a soluble viral protein. It is found early in the course of acute hepatitis B and disappears soon after ALT peaks. Persistence of HBeAg beyond 3 months after the onset of illness is unusual and may suggest progression to chronic infection.
What is HBeAg and HBeAb?
Abstract. In chronic hepatitis B virus (HBV) infection seroconversion from hepatitis B e antigen (HBeAg) to hepatitis B e antibody (HBeAb) may be followed either by remission of the disease with low-level viraemia, or by continuing inflammation with high-level viraemia.
What is e antigen negative hepatitis B?
Hepatitis B e antigen (HBeAg)-negative chronic hepatitis B (CHB) occurs at the late phase in hepatitis B virus (HBV) infection’s natural history. The disease is characterized by progressive liver damage due to variants with mutations in the precore/core promoter region that reduce or abolish HBeAg expression.
How long do hepatitis B antibodies last?
Understand that hepatitis B vaccination-induced protective antibodies can last for up to 15 years, but appear to fall off over time. Patients who were vaccinated 10 to 15 years ago, especially those who were vaccinated as children, may not be adequately protected.
What is normal HBsAg value?
Any value between 1 and 5 s/c is indeterminate and should be repeated. For hepatitis B surface antibody (anti-HBs), a level less than 5 mIU is considered negative, while a level more than 12 mIU is considered protective. Any value between 5 and 12 mIU is indeterminate and should be repeated.
What does a positive Hbeab mean?
What HBeAg Test Results Mean. A positive test for the hepatitis B e-antigen means that there is an active infection with the hepatitis B virus and the virus is actively multiplying. Anyone who is in contact with your blood without protection may be at risk of contracting hepatitis B from you.
What does a positive HBeAb mean?
What is the difference between HBeAg positive and HBeAg negative?
In HBV carriers and patients with chronic hepatitis B, positive HBeAg results usually indicate presence of active HBV replication and high infectivity. A negative HBeAg result indicates very minimal or no HBV replication. Positive anti-HBe results usually indicate inactivity of the virus and low infectivity.
What does HBe antigen negative mean?
A negative HBeAg result indicates very minimal or no HBV replication. Positive anti-HBe results usually indicate inactivity of the virus and low infectivity. Positive anti-HBe results in the presence of detectable HBV DNA in serum also indicate active viral replication in these patients.
Can you lose hepatitis B immunity?
The duration of immunity after vaccination against HBV is not known. Ten percent of the patients who receive and respond to vaccination lose anti-HBs after 5 years and 50% lose anti-HBs after 10 years.
