Can ketones undergo condensation?
Can ketones undergo condensation?
The aldol condensation of ketones with aryl aldehydes to form α,β-unsaturated derivatives is called the Claisen-Schmidt reaction.
What is ketone condensation?
Aldol condensation: An addition reaction between two aldehydes, two ketones, or an aldehyde and a ketone, resulting in a β-hydroxy aldehyde or a β-hydroxy ketone. Subsequent dehydration produces an α,β-unsaturated aldehyde or ketone. A crossed aldol condensation uses two different aldehyde and/or ketone reactants.
What is meant by a condensation reaction?
condensation reaction, any of a class of reactions in which two molecules combine, usually in the presence of a catalyst, with elimination of water or some other simple molecule.
What gives aldol condensation?
Aldol condensation occurs in aldehydes having α-hydrogen with a dilute base to give β-hydroxy aldehydes called aldols. This reaction is most commonly known as aldol condensation. If the condensation reaction occurs between two different carbonyl compounds it is called crossed aldol condensation.
Does propanone give aldol condensation?
Propanone aldol condensation First gives the aldol product with dilute NaOH or KOH. Then aldol product is heated alone or heated with I2. Alcohol group in the aldol product is eliminated (dehydration) by forming a double bond.
What type of reaction occurs in an aldol condensation?
An aldol condensation is a condensation reaction in organic chemistry in which an enol or an enolate ion reacts with a carbonyl compound to form a β-hydroxyaldehyde or β-hydroxyketone, followed by dehydration to give a conjugated enone.
What is an example of a condensation reaction?
Common examples include the aldol condensation and the Knoevenagel condensation, which both form water as a by-product, as well as the Claisen condensation and the Dieckman condensation (intramolecular Claisen condensation), which form alcohols as by-products.
What kind of reaction is the Crossed Claisen condensation?
The ‘crossed’ Claisen condensation reaction (also known as mixed Claisen condensation), where one of the molecules is an enolizable ester and the other is a ketone or a non-enolizable ester. The Dieckmann condensation reaction, in which a molecule featuring two ester groups undergoes an intramolecular reaction.
What happens when a ketone is used with an enolizable ester?
When an enolizable ester/ketone is used with a non-enolizable ester, the resulting reaction is known as the crossed Claisen condensation. Another modification of this reaction is the Stobbe condensation reaction, which can proceed with relatively weaker bases.
Which is a result of the carbonyl condensation reaction?
Carbonyl Condensation Reactions. As a result of the large dipole of the carbonyl group: 1. The carbonyl carbon is electrophilic and is the site of addition reactions by nucleophiles; 2. The α-protons are acidic and can be deprotonated by strong bases to give an enolate, which are nucleophiles and react with electrophiles.
What is the structure of the Dieckmann condensation reaction?
The Dieckmann condensation reaction involves the intramolecular reactions of two ester groups belonging to the same molecule. The reaction yields a beta-keto ester which has a cyclic structure.
