What is MultiHance injection used for?
What is MultiHance injection used for?
MultiHance is indicated for intravenous use in magnetic resonance imaging (MRI) of the central nervous system (CNS) in adults and pediatric patients (including term neonates), to visualize lesions with abnormal blood-brain barrier or abnormal vascularity of the brain, spine, and associated tissues.
Is MultiHance safe?
Conclusions: MultiHance appears to be well tolerated in adults and children and in subjects with impaired liver or kidney function or coronary artery disease. In controlled trials, MultiHance demonstrated a similar safety profile to that of Magnevist.
Who manufactures MultiHance?
MultiHance is manufactured for Bracco Diagnostics Inc. by BIPSO GmbH – 78224 Singen (Germany) and by Patheon Italia S.p.A., Ferentino, Italy. MultiHance is a registered trademark of Bracco International B.V.
What type of contrast is MultiHance?
MultiHance is a paramagnetic contrast agent for use in diagnostic magnetic resonance imaging (MRI) of the liver in adults and children (above the age of 2 years).
Is MultiHance a gadolinium?
MultiHance is a sterile, nonpyrogenic, clear, colorless aqueous solution for intravenous use only, containing 529 mg gadobenate dimeglumine per mL. MultiHance is contraindicated in patients with known allergic or hypersensitivity reactions to gadolinium-based contrast agents [see Warnings and Precautions (5.2)].
Is MultiHance ionic or nonionic?
Table 1. Characteristics of Gadolinium-based Contrast Agents
| Generic Name | Trade Name | Structure |
|---|---|---|
| Gadodiamide | Omniscan | Linear nonionic |
| Gadoversetamide | Optimark | Linear nonionic |
| Gadopentetate dimeglumine | Magnevist | Linear ionic |
| Gadobenate dimeglumine | MultiHance | Linear ionic |
Is MultiHance linear or macrocyclic?
MultiHance, the high-relaxivity linear agent, is considered intermediate-stability, while the conventional-relaxivity, linear agents have the lowest stability, with the greatest propensity to release gadolinium, albeit in trace amounts with no indication of clinical consequences.
Is DOTAREM safer than gadolinium?
The U.S. Food and Drug Administration has approved Dotarem as safe for use in MRI scans. However, patients with severe kidney disease or gadolinium contrast allergy should consult with their radiologist before receiving gadolinium contrast.
Is DOTAREM safe for kidneys?
Dotarem can cause a life-threatening condition in people with advanced kidney disease. You should not receive this medicine if you have kidney disease or if you are on dialysis. Gadoterate meglumine can stay in your body for months or years after you receive this medicine.
How do I detox my body from gadolinium?
How do I detox my body from gadolinium? We have found that chelation therapy and the use of specific oral supplements is the best detox for most patients. Chelation is especially valuable – a procedure which uses a specific binding agent to capture and remove gadolinium from the body.
What does gadolinium do to the brain?
Gadolinium enhances the quality of MRI by altering the magnetic properties of water molecules that are nearby in the body. Gadolinium can improve the visibility of specific organs, blood vessels, or tissues and is used to detect and characterize disruptions in normal physiology.
How much gadobenate is in a mL of MultiHance?
MultiHance injection is supplied as a sterile, nonpyrogenic, clear, colorless to slightly yellow aqueous solution intended for intravenous use only. Each mL of MultiHance contains 529 mg gadobenate dimeglumine and water for injection.
What do you need to know about MultiHance injection?
Magnetic resonance angiography (MRA) to evaluate adults with known or suspected renal or aorto-ilio-femoral occlusive vascular disease. 1. MultiHance (gadobenate dimeglumine) injection, 529 mg/mL full Prescribing Information. Monroe Twp., NJ: Bracco Diagnostics Inc. August 2018. 2. ACR Manual on Contrast Media, Version 10.3, 2020.
When to use MultiHance vials for single use?
MultiHance vials are intended for single use only. Administer immediately after opening and discard any unused product. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
What kind of aqueous solution is MultiHance?
MultiHance is a sterile, nonpyrogenic, clear, colorless to slightly yellow aqueous solution for intravenous use only, containing 529 mg gadobenate dimeglumine per mL. MultiHance (gadobenate dimeglumine) is a clear, colorless to slightly yellow solution containing 529 mg gadobenate dimeglumine per mL.
