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Is UniProt a protein database?

Is UniProt a protein database?

UniProt is a freely accessible database of protein sequence and functional information, many entries being derived from genome sequencing projects. It contains a large amount of information about the biological function of proteins derived from the research literature.

What is OmpF protein?

Background: OmpF porin is a trimeric integral membrane protein responsible for the passive transport of small hydrophilic molecules, such as nutrients and waste products, across the outer membrane of Escherichia coli. The trimer structure is virtually identical in both.

Where is protein sequence in UniProt?

Retrieving sequences from the website

  1. Perform your favorite query and view the resulting list of entries (e.g. this query retrieves all UniProtKB entries that are part of the human proteome: proteome:UP000005640)
  2. Click the Download button in the query result page.

How many protein sequences are in UniProt?

UniProtKB/Swiss-Prot has curated over 81 000 variants in 13,000 human protein sequence records from peer-reviewed literature, annotated with information on the functional impact and clinical significance, when known.

What kind of database is UniProt?

The Universal Protein Resource (UniProt) is a comprehensive resource for protein sequence and annotation data. The UniProt databases are the UniProt Knowledgebase (UniProtKB), the UniProt Reference Clusters (UniRef), and the UniProt Archive (UniParc).

Is OMPF a porin?

OmpF porin is a nonspecific pore protein from the outer membrane of Escherichia coli.

What does OMPF mean?

Official Military Personnel File
Personnel Record Portion: The Official Military Personnel File (OMPF) is primarily an administrative record, containing information about the subject’s service history such as: date and type of enlistment/appointment; duty stations and assignments; training, qualifications, performance; awards and decorations received; …

Which component of UniProt cover well studied model organism and phylogeny?

Reference proteomes
Reference proteomes constitute a representative cross-section of the taxonomic diversity to be found within UniProtKB. They include the proteomes of well-studied model organisms and other proteomes of interest for biomedical and biotechnological research.

What is the use of UniProt?

UniProt is the central resource for storing and interconnecting information from large and disparate sources, and the most comprehensive catalog of protein sequence and functional annotation.

Is UniProt a primary database or secondary?

Many data resources have both primary and secondary characteristics. For example, UniProt accepts primary sequences derived from peptide sequencing experiments.

Is UniProt and Swiss-Prot same?

UniProt provides a comprehensive, high-quality and freely accessible resource of protein sequence and functional information. UniProtKB/Swiss-Prot is a high quality manually annotated (reviewed) and non- redundant protein sequence database, which brings together experimental results and computed features.

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Ruth Doyle