How do you prescribe Cathflo?

How do you prescribe Cathflo?

After WASHING hands using aseptic technique, reconstitute Cathflo to a final concentration of 2 mg/2 mL:

1. Aseptically WITHDRAW 2.2 mL of Sterile Water for Injection, USP (diluent is not provided).
2. INJECT the 2.2 mL of Sterile Water for Injection, USP, into the Cathflo vial, directing the diluent stream into the powder.

How do you administer Cathflo Activase?

Inject the 2.2 mL of Sterile Water for Injection, USP, into the Cathflo Activase vial, directing the diluent stream into the powder. Slight foaming is not unusual; let the vial stand undisturbed to allow large bubbles to dissipate. Mix by gently swirling until the contents are completely dissolved.

How do you administer alteplase to a PICC line?

Doses of 1 to 2 mg injected into the lumen(s) of central venous catheters or PICC lines, allowed to dwell for 15 minutes to 4 hours, then removed by aspiration, have been reported effective in establishing patency. Instill 2 mg/2 ml into the dysfunctional catheter for 2 hours.

Who makes Cathflo Activase?

2008;12(6):925-934. Cathflo Prescribing Information. Genentech USA, Inc.

Is Cathflo the same as tPA?

TPA, Activase, and Cathflo Activase are brand names available for alteplase.

Can Cathflo cause bleeding?

Common side effects of Cathflo Activase include: bleeding (may be serious), blood clots, and. infection.

How do I make tPA?

Hold the water vial firmly in the upright position. With your other hand hold the tPA upside down, and lower the vial down onto the spike. With both vials firmly spiked, invert both vials together. At this point, the water will on top and will flow from the water vial into the tPA vial.

Can you use alteplase for PICC line?

One serious adverse event (fever) was attributed to study drug. Conclusions: Treatment with use of a maximum of two doses of alteplase is safe and effective in restoring function to occluded PICCs.

How is alteplase administered?

Alteplase is administered intravenously at a concentration of 1 mg/mL for the treatment of acute ischemic stroke, pulmonary embolism, and myocardial infarction. The reconstituted solution is stable for 8 hours at room temperature.

Is Cathflo the same as TPA?

What is Cathflo made of?

Each vial of Cathflo Activase contains 2.2 mg of Alteplase (which includes a 10% overfill), 77 mg of L-arginine, 0.2 mg of polysorbate 80, and phosphoric acid for pH adjustment. Each reconstituted vial will deliver 2 mg of Cathflo Activase, at a pH of approximately 7.3.

Who makes tPA drug?

Genentech: Activase® (alteplase) – Information for Patients.

What do you need to know about cathflo activase?

Cathflo Activase Description. Cathflo® Activase® (Alteplase) is a tissue plasminogen activator (t‑PA) produced by recombinant DNA technology. It is a sterile, purified glycoprotein of 527 amino acids.

What kind of powder is used for cathflo injection?

Cathflo Activase (Alteplase) for injection is a sterile, white to pale yellow, lyophilized powder for intracatheter instillation for restoration of function to central venous access devices following reconstitution with Sterile Water for Injection, USP.

What’s the dosage of cathflo for catheter instillation?

Cathflo Activase Dosage and Administration Cathflo ® Activase ® (Alteplase) is for instillation into the dysfunctional catheter at a concentration of 1 mg/mL. If catheter function is not restored at 120 minutes after 1 dose of Cathflo Activase, a second dose may be instilled (see Instructions for Administration).

How do I get a replacement for cathflo?

For spoiled product, please complete the Spoilage Program online form for Cathflo. My Cathflo is spoiled, expired, or damaged, how do I get a replacement? For spoiled product, please complete the Spoilage Program online form for Cathflo.