What do margins mean in prostate cancer?
What do margins mean in prostate cancer?
The ink that was painted onto the edge of the prostate can also be seen and this helps the pathologist know which part of the prostate the sample came from. This coloured ink marks the outside edges of the prostate gland and is known as the surgical margins.
What is meant by resection margins?
[1] Resection margin or surgical margin as defined by Hinni et al. is any tissue plane where the surgeon’s knife meets the patient. [2] During surgical removal, the palpable or visible tumor is resected with a fringe of normal tissue to ensure complete removal of tumor.
What does positive margins mean in biopsy?
Positive: Cancer cells come right out to the edge of the removed tissue. More surgery is usually needed to remove any remaining cancer cells. Close: Cancer cells are close to the edge of the tissue, but not right at the edge. More surgery may be needed.
Does clear margins mean cancer free?
A clear, negative, or clean margin means there are no cancer cells at the outer edge of tissue that was removed. A positive margin means that cancer cells come right out to the edge of the removed tissue and have ink on them.
How do pathologists examine surgical margins?
Apart from traditional methods looking at stained “shaves” (thin slices of tissue removed from the edge of the margin) or smeared and stained imprints, more recent techniques used to assess margins include x-rays with compression, frozen specimens, and new techniques such as optical coherence tomography and …
What is a negative margin?
Gross profit margin can turn negative when the costs of production exceed total sales. A negative margin can be an indication of a company’s inability to control costs. Gross profit is the revenue earned by a company after deducting the direct costs of producing its products.
What does extending to the deep margin mean?
DEEP MARGIN: Involved by invasive melanoma. If melanoma extends to the edge of the sample (the margins), then it is presumed that the biopsy or excision did not remove the entire tumor. Deep margins are located at the base of the biopsy/specimen and lateral/peripheral margins are the side edges of the biopsy/specimen.
Why radiation if margins are clear?
Clear margins offer the lowest risk of recurrence in the same breast; wider clear margins don’t reduce this risk any further. Treatments after surgery (called adjuvant treatments by doctors), such as hormonal therapy, radiation therapy, and chemotherapy, reduce the risk of recurrence in the same breast.
What does deep margin involved mean?
DEEP MARGIN: Involved by invasive melanoma. Deep margins are located at the base of the biopsy/specimen and lateral/peripheral margins are the side edges of the biopsy/specimen. If there is no tumor extending to the margins, the pathologist will describe how close the lesion came to the edge.
What is lateral margin?
[TA] the margin or edge of a structure that is farthest from the midline.
What does a positive surgical margin mean for prostate cancer?
So that we are very clear, a positive surgical margin is an area on the edge of the prostate specimen, after surgical removal, that stains positive for prostate cancer cells when it is tested in the pathology laboratory. The implication being that the surgeon may have cut too…
What is the risk of prostate cancer after surgery?
Positive Margins After Surgery for Prostate Cancer. The presence of a positive margin can be more or less serious depending on the Gleason score and the extent of the positive margins. Across the board, the average risk of future cancer relapse in men with positive margins is about 50 percent.
What are the chances of prostate cancer relapse?
The presence of a positive margin can be more or less serious depending on the Gleason score and the extent of the positive margins. Across the board, the average risk of future cancer relapse in men with positive margins is about 50 percent.
When do you know if you have positive surgical margins?
Under most circumstances the presence of one or more positive surgical margins is revealed when the pathology report returns a few days after surgery.
