What does multifocal mean in breast cancer?
What does multifocal mean in breast cancer?
Listen to pronunciation. (mul-tee-FOH-kul brest KAN-ser) Breast cancer in which there is more than one tumor, all of which have arisen from one original tumor. The tumors are likely to be in the same quadrant (section) of the breast.
What is the treatment for multifocal breast cancer?
There are several treatment options available for multifocal breast cancer. These include lumpectomy, mastectomy, radiation therapy, hormonal therapy, and chemotherapy.
Is multifocal breast cancer common?
Multifocal and multicentric breast cancer (MMBC) is common, with a reported incidence of 9–75%. Incidence varies according to the extent of breast tissue sampling, but this wide range of reported incidence also reflects the lack of a standard definition of MMBC.
What is multifocal in cancer?
Multifocal breast cancer occurs when there are two or more tumors in the same breast. All of the tumors begin in one original tumor. The tumors are also all in the same quadrant — or section — of the breast. Multicentric breast cancer is a similar type of cancer.
Is multifocal breast cancer worse?
Our findings suggest that multifocal/multicentric disease may be associated with worse outcomes versus unifocal disease regardless of type of surgery. This suggests a more biologically aggressive cancer and may be an important consideration when managing these patients.
What do multifocal mean?
Definition of multifocal : having multiple foci: such as. a of a disease : arising from or present in more than one location or localized area of the body multifocal pneumonia with infiltrates throughout both lungs …
What does multicentric mean?
: having multiple centers of origin a multicentric tumor.
Is multifocal the same as varifocal?
Multifocal contact lenses are also known as varifocal lenses and have many benefits for those with presbyopia by correcting age-related vision problems when their eyes can no longer focus on objects up close. Multifocal contact lenses (multifocal contacts) are also known as ‘progressive contact lenses’.
What is ductal carcinoma in situ?
Ductal carcinoma in situ (DCIS) means the cells that line the milk ducts of the breast have become cancer, but they have not spread into surrounding breast tissue. DCIS is considered non-invasive or pre-invasive breast cancer.
What do you need to know about multifocal breast cancer?
Multicentric breast cancer, where at least two tumors develop separately, often in different areas of the breast. Multifocal breast cancer is not necessarily more advanced or aggressive than single tumor breast cancer. Staging multifocal breast cancer depends primarily upon the characteristics of the primary, or largest, tumor.
What is the importance of multifocal / multicentric tumor?
The importance of multifocal/multicentric tumor on the disease-free survival of breast cancer patients: single center experience M/M imparts an unfavorable prognosis on the DFS of breast cancer patients in comparison to unifocal tumors and the presence of multifocal/multicentric tumors were associated with advanced pT and pN stages.
Which is worse a multifocal or unifocal tumor?
As tumor size increased and the number of axillary lymph nodes metastasis increased, the incidence of M/M increased significantly (P=0.003 vs. P=0.02, respectively). Overall, the median DFS time of patients with multifocal/multicentric tumors was significantly worse than that of the unifocal tumors (55 vs. 137 mo, P<0.001).
How is aggregate dimension used in breast cancer?
The use of aggregate dimension reclassified significant numbers of multifocal tumors at a more advanced stage. Use of this method to stage cancers, rather than the largest tumor size, removed the excess node positivity when compared with unifocal, stage-matched breast carcinomas.
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