What does HSV equivocal mean?
What does HSV equivocal mean?
Herpes Simplex Virus Type 1 and/or 2 Antibodies, IgM. Less than 0.90: Negative. 0.90 – 1.09 IV: Equivocal – Repeat testing in 10-14 days may be helpful. Greater than 1.09: Positive – May indicate a current or recent infection.
How accurate are HSV urine tests?
The cutoff for a positive result on the HerpeSelect test, manufactured by Quest Diagnostics, is 1.1. A 2005 study published in the journal BioMed Central Infectious Disease found that index values above 3.5 yielded over 90 percent accuracy — but scores between 1.1 and 3.5 had around a 50 percent chance of being wrong.
How accurate is PCR HSV test?
PCR assays or other NAATs are the most sensitive test currently available to detect HSV in clinical samples. The detection rates of the PCR assays were shown to be 11–71% superior to virus culture [26,41-44].
What causes HSV to reactivate?
Herpes simplex virus (HSV) establishes a latent infection in peripheral neurons and can periodically reactivate to cause disease. Reactivation can be triggered by a variety of stimuli that activate different cellular processes to result in increased HSV lytic gene expression and production of infectious virus.
Does equivocal mean positive?
Equivocal antibody test results mean that the results could not be interpreted as positive or negative. Reasons for this may include: There is an immune response but it’s not strong enough to give a positive result. You may have had an infection in the past caused by another virus in the coronavirus family.
What does HSV 0.91 mean?
Test results for herpes fall within a numeric range. If your test returns a value of 0.91 or below you are negative. A value of 1.09 or above is a positive.
Does everyone have HSV-1 antibodies?
Tests can be done to help determine if you have a recent infection. About 70% of adults have been infected by HSV-1 and have antibodies against the virus. About 20 to 50% of adults will have antibodies against the HSV-2 virus, which causes genital herpes. HSV stays in your system once you have been infected.
Can you get a false positive HSV 1 Test?
Meanwhile, the CDC and the US Preventive Services Task Force concur that the most widely available herpes test, called HerpeSelect, should not be used to screen asymptomatic people because of its high risk of false positives: Up to 1 in 2 positive tests could be false, according to the USPSTF’s most recent guidelines.
What is a low positive for HSV 2?
If HSV-2 IgG type specific antibodies patient results fall between 0.91 (equivocal) and 5.00 (low positive) index values, the specimen will reflex to HSV-2 supplemental test per CDC guidelines.
What does .90 mean on STD test?
The reference range indicates whether the STD value is high enough to be considered positive; if not, it returns negative. For example, a range of < 0.90 in the “Herpes Simplex-2” test means any results below the 0.90 range are considered negative.
