What do you give for status epilepticus?
What do you give for status epilepticus?
The benzodiazepines most commonly used to treat status epilepticus are diazepam (Valium), lorazepam (Ativan), and midazolam (Versed).
Does Thiopentone cause bradycardia?
With the introduction of thiopentone the seizures could be controlled but the patient developed severe bradycardia and junctional rhythm. The bradycardia disappeared when thiopentone was withdrawn and reappeared when the drug was reintroduced.
What is thiopental used for?
Thiopental sodium is used for the induction of general anaesthesia and is also used as an adjunct to provide hypnosis during balanced anaesthesia with other anaesthetic agents, including analgesics and muscle relaxants.
Which medication has been effective in treating status epilepticus that is refractory to phenobarbital?
Lorazepam is the most commonly used agent, used at a dose of 0.1 mg/kg given in dose of 2 mg/min to a maximum of 8 mg. Lorazepam was shown to be successful in 64.9% patients as the first line compared to 58.2% success with phenobarbital and 55.8 % with Diazepam plus Phenytoin.
What is the immediate IV treatment for status epilepticus?
In the stabilization phase, standard first-aid for seizures should be initiated. In the initial therapy phase, a benzodiazepine (specifically IM midazolam, IV lorazepam, or IV diazepam) is recommended as initial therapy. In the second phase, options include IV fosphenytoin, valproic acid, or levetiracetam.
Does Thiopentone cause hypotension?
3,4 The induction dose of Thiopentone is 3-5 mg/kg, with dose-dependant hypotension as it’s usual side effect due to decrease in myocardial contractility as well as peripheral vasodilation.
Why is thiopental used in RSI?
Thiopental provides rapid loss of consciousness at a predictable dose (3–7 mg kg−1) with a clearly defined end-point. It is noticeably quicker than both etomidate and propofol. However, it has a longer duration of action and its side effects are potentially life-threatening.
How do you dilute Thiopentone?
Solutions may be prepared by adding thiopental to 5% water solution of dextrose or to 0.9% solution of sodium chloride.
How long does sodium thiopental take to work?
Sodium thiopental
| Clinical data | |
|---|---|
| Onset of action | 30–45 seconds |
| Elimination half-life | 5.5–26 hours |
| Duration of action | 5–10 minutes |
| Identifiers |
Why is lorazepam used to treat seizures?
Ativan binds to a type of GABA receptor, called GABAA, and activates it in a similar way to GABA. GABA is a signaling molecule that inhibits nerve cell signaling. Through this mechanism, Ativan is thought to reduce the uncontrolled firing of neurons that causes seizures.
What is the purpose of phenytoin sodium?
Phenytoin is used to control certain type of seizures, and to treat and prevent seizures that may begin during or after surgery to the brain or nervous system. Phenytoin is in a class of medications called anticonvulsants. It works by decreasing abnormal electrical activity in the brain.
