Is Kell a blood type?

Is Kell a blood type?

Chapter 8The Kell blood group. The Kell blood group system is complex and contains many antigens that are highly immunogenic. These antigens are the third most potent, after those of the ABO and Rh blood groups, at triggering an immune reaction.

What is Kell factor in blood?

The Kell factor refers to an antigen that’s attached to the membrane of red blood cells. Some people have it; some don’t. And generally, that’s not a problem. But a problem can occur when a Kell-negative mom is somehow exposed to the Kell-positive blood — say, via a blood transfusion.

What is MNS blood group?

MNS was the second blood group, discovered in 1927, after immunizing rabbits with human RBCs. The M and N antigens were identified first, but it was another 20 years before the S and s antigens were named. Now, more than 40 antigens are known in this blood group, but the M, N, S, and s antigens remain the most common.

How many people have the K antigen?

The K antigen is present in about 9% of whites and is responsible for 10% of cases of severe HDFN.

How do you get anti-Kell antibodies?

Over half of the cases of hemolytic disease of the newborn owing the anti-Kell antibodies are caused by multiple blood transfusions, with the remainder due to a previous pregnancy with a Kell1 positive baby.

How common is k blood type?

The red cells of 9% of the Caucasian population have the K antigen on their surface. After the Rh antigens, anti-K is the most common antibody found in testing patients prior to transfusion. Another blood group, Kidd, was named after the patient in whom it was discovered.

What is the Lewis blood group?

Lewis blood group system, classification of human blood based on the expression of glycoproteins called Lewis (Le) antigens on the surfaces of red blood cells or in body fluids, or both.

How rare is the K antigen?

Commonly but imprecisely called “Kell,” this is the most important antigen in the Kell blood group system. This antigen also goes by the name “KEL1.” While K is a relatively low-frequency antigen (present in only about 9% of Caucasians and 2% of African-Americans), it is very important for several reasons.

What does Kell blood-group system mean?

The Kell antigen system (also known as Kell-Cellano system) is a human blood group system , that is, group of antigens on the human red blood cell surface which are important determinants of blood type and are targets for autoimmune or alloimmune diseases which destroy red blood cells. Kell can be noted as K, k, or Kp.

What is Kell antibody?

Kell Antibody (3H571) is a mouse monoclonal IgG 1 (kappa light chain) provided at 200 µg/ml. raised against erythrocytes of human origin. recommended for detection of the Kell blood group antigen Kpbc and Kp (a+b-c+) and Kp (a-b-c+) erythrocytes of human origin by IP; non cross-reactive with Ko erythrocytes.

What is the human blood group system?

The term human blood group systems is defined by International Society of Blood Transfusion as systems in the human species where cell-surface antigens —in particular, those on blood cells—are “controlled at a single gene locus or by two or more very closely linked homologous genes with little or no observable…