Can you take entecavir while pregnant?

Can you take entecavir while pregnant?

Entecavir, however, is contraindicated in pregnancy use due to its significant carcinogenic potential in animal studies [8, 9]. There are sufficient safety reports on the safety of TDF use during pregnancy [34]. TDF is increasingly recommended due to its lowest risk of viral resistance with continuous therapy [8, 9].

What happens if you stop entecavir?

If you experience any of the following symptoms after you stop taking entecavir, call your doctor immediately: extreme tiredness, weakness, nausea, vomiting, loss of appetite, yellowing of the skin or eyes, dark-colored urine, light-colored bowel movements, or muscle or joint pain.

Can a pregnant woman take hepatitis B drugs?

To minimize fetal exposure to antiviral agents, antiviral therapy during pregnancy should be reserved for mothers with advanced disease or who are at risk for hepatic decompensation. Current safety data suggest that lamivudine, telbivudine, or tenofovir may be used during pregnancy.

How does hepatitis B affect pregnancy?

About 9 in 10 pregnant women with acute hepatitis B virus infection will pass the virus to their babies. Between 1 and 2 in 10 women with chronic infection will do so. The baby can get the virus by being exposed to infected blood and fluids during labor and delivery.

Can you stop taking hepatitis B medication?

EASL guidelines say non-cirrhotic, HBeAg-negative patients who have had at least three years of antiviral treatment, undetectable viral load and no signs of liver damage can stop treatment, as long as there is frequent follow-up monitoring.

How can I reduce my hepatitis B viral load?

Several antiviral medications — including entecavir (Baraclude), tenofovir (Viread), lamivudine (Epivir), adefovir (Hepsera) and telbivudine (Tyzeka) — can help fight the virus and slow its ability to damage your liver. These drugs are taken by mouth. Talk to your doctor about which medication might be right for you.

Can I pass hepatitis B to my baby?

Hepatitis B can be easily passed from a pregnant woman with hepatitis B to her baby at birth. This can happen during a vaginal delivery or a c-section. If you have hepatitis B, health care providers can give your baby a set of shots at birth to prevent your baby from getting infected.

What are the risks of taking entecavir during pregnancy?

Entecavir Pregnancy Warnings. Maternal and embryofetal toxicity were not seen with oral doses ranging from 28 to 212 times the highest human exposure (1 mg/day); maternal toxicity, embryofetal toxicity, skeletal malformations, and/or decreased fetal weights were observed with exposures ranging from 883 to 3100 times those in humans.

What happens to your body when you stop taking entecavir?

You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. Call your doctor or get emergency medical help if you have unusual muscle pain, trouble breathing, stomach pain, dizziness, feeling cold, or feeling very weak or tired. Hepatitis B may become active or get worse after you stop using entecavir.

When is the best time to take entecavir?

Take entecavir on an empty stomach, at least 2 hours before or 2 hours after eating. Measure liquid medicine carefully, using the dosing syringe with your medicine (not a kitchen spoon). Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

Is it safe to share a needle with entecavir?

Sharing drug or medicine needles is never safe, even for a healthy person. Other drugs may interact with entecavir, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.