What does phrynoderma mean?
What does phrynoderma mean?
[ frĭn′ə-dûr′mə ] n. A follicular hyperkeratotic eruption that is associated with vitamin A deficiency.
What causes phrynoderma?
In developed countries, phrynoderma most often occurs as a result of malabsorption due to surgical or medical causes, such as small-bowel bypass surgery, colectomy and pancreatic insufficiency.
What is phrynoderma biochemistry?
These studies would indicate that phrynoderma is a manifestation of essential fatty acid deficiency and vitamins of the B-complex group play a significant role in the etiology and treatment of the condition.
What is phrynoderma nutrition?
Phrynoderma is a distinctive form of follicular hyperkeratosis associated with nutritional deficiency. Although originally thought to represent vitamin A deficiency, several studies have demonstrated multiple etiologies.
Is Phrynoderma itchy?
The lesions were asymptomatic in 114 (91.2%) patients and mild itching was present in 11 (8.8%) patients. The distribution of lesions was bilateral and symmetrical in 89 (71.2%) patients.
What is EFA deficiency?
Essential fatty acid (EFA) deficiency is rare, occurring most often in infants fed diets deficient in EFAs. Signs include scaly dermatitis, alopecia, thrombocytopenia, and, in children, intellectual disability. Diagnosis is clinical. Dietary replenishment of EFAs reverses the deficiency.
Is pruritus a symptom?
Itching on the whole body might be a symptom of an underlying illness, such as liver disease, kidney disease, anemia, diabetes, thyroid problems, multiple myeloma or lymphoma. Nerve disorders. Examples include multiple sclerosis, pinched nerves and shingles (herpes zoster). Psychiatric conditions.
Should I be worried about Beau’s lines?
Deep horizontal ridges, called Beau’s lines, are often symptoms of a serious condition. They may actually stop nail growth until the underlying condition is treated. Acute kidney disease may also be present if Beau’s lines appear.
What are signs of zinc deficiency?
Symptoms
- unexplained weight loss.
- wounds that won’t heal.
- lack of alertness.
- decreased sense of smell and taste.
- diarrhea.
- loss of appetite.
- open sores on the skin.
How is EFA deficiency treated?
The EFA deficiency was reversed after 21 days by daily, topical application of linoleic acid to the patient’s skin. The ratio of eicosatrienoic acid (20:3, n-9) to eicosatetraenoic acid (20:4, n-6) decreased to normal levels in the skin and serum with clinical improvement of the EFA deficiency syndrome.
When to use phrynoderma as a differential diagnosis?
Phrynoderma must be considered in the differential diagnosis in patients with extensor surface hyperkeratotic papules and plaques in the setting of malnourishment and should prompt the clinician to evaluate cell markers of nutritional status, not just vitamin A.
What kind of skin condition is phrynoderma?
Phrynoderma is a form of asymptomatic or mildly symptomatic follicular hyperkeratosis, where follicular papules of various sizes with central keratotic plugs that block the follicle openings develop on the skin [1]. New patches may be hypopigmented [3,4].
How is phrynoderma a manifestation of vitamin A deficiency?
Characteristic skin lesions are hyperkeratotic papules that first appear on the … Phrynoderma is a distinctive form of follicular hyperkeratosis associated with nutritional deficiency. Although originally thought to represent vitamin A deficiency, several studies have demonstrated multiple etiologies.
Who is most at risk for getting phrynoderma?
Phrynoderma is a form of follicular hyperkeratosis associated with nutritional deficiency. Who gets phrynoderma? Phrynoderma is most often reported in children living in poverty in Africa and Asia. A dietary history may reveal: Lack of vegetables, fruit and fat in the diet.
