What is radial intercalation?
What is radial intercalation? Radial intercalation, in which cells exchange places throughout the thickness of a multilayered tissue, can drive tissue spreading, or epiboly. Radial intercalation occurs during frog and fish gastrulation, as well as during thinning of the ventral mesoderm in Drosophila and development of skin in frogs (Figure 1A). What is Epiboly in biology? Epiboly is a morphogenetic process that is employed in the surface ectoderm of anamniotes during gastrulation to cover the entire embryo. We propose here that mammals also utilise this process to expand the epidermis and enclose the body cavity and spinal cord with a...