What causes guanidinoacetate methyltransferase deficiency?
What causes guanidinoacetate methyltransferase deficiency? Guanidinoacetate methyltransferase (GAMT) deficiency is caused by changes ( mutations ) in the GAMT gene . This gene provides instructions to the body to create a substance called creatine. Creatine helps the body store and use energy properly. What is guanidinoacetate? Guanidinoacetate methyltransferase deficiency (GAMT) is one of the three cerebral creatine deficiency syndromes (CCDS). These conditions are inborn errors of creatine metabolism which interrupt the formation or transportation of creatine. What nutritional supplement is synthesized by the kidneys liver and pancreas? Creatine is an amino acid located mostly in your body's muscles as well...