Can ALDH2 deficiency be treated?
Can ALDH2 deficiency be treated? New Rochelle, NY, February 12, 2020--A new study has shown that gene therapy to treat one of the most common hereditary disorders, aldehyde dehydrogenase type 2 (ALDH2) deficiency, may prevent increased risk for esophageal cancer and osteoporosis associated with chronic alcohol exposure. What causes low ALDH? In people with alcohol intolerance, a genetic mutation (change) makes ALDH2 less active or inactive. As a result, your body can't convert acetaldehyde to acetic acid. Acetaldehyde starts to build up in your blood and tissues, causing symptoms. What happens if ALDH2 is not working properly? ALDH2 deficiency, more...