What is Delta Delta CT in qPCR?
What is Delta Delta CT in qPCR? The delta-delta Ct method, also known as the 2–∆∆Ct method, is a simple formula used in order to calculate the relative fold gene expression of samples when performing real-time polymerase chain reaction (also known as qPCR). What does Delta CT tell you? Delta Ct corresponds to the difference between CtSOI and Ct of your reference sequence (RS), a house keeping gene sequence usually. Delta Ct shows the difference of expression between 2 genes whereas Ct is specific to the expression of one gene. How do you analyze qPCR results? There are two main...